Learning points - This is a case of 65 year old female with Generalised Tonic Clinic seizures Osce questions 1) Reasons for seizures in old age people * Neurodegenerative disorders * Cerebrovascular disorders * Dementia * Metabolic disorders - Hypoglycemia - electrolyte imbalances - uraemia * Physical or mental exhaustion 2) pathophysiology of seizures * To function normally brain must maintain a continual balance between excitation and inhibition , remaining responsive to environment while avoiding continued unrestrained spontaneous activity * GABA inhibitory neurotransmitter acts on ion channels , enhances inflow of chloride and reduces formation of action potential * Excitatory amino acids allow influx of sodium and calcium and producing opposite effects * It is likely that many seizures results from an imbalance between this excitation and inhibition. ( From Davidson medicine text book ) 3) Drug of choice for different seizure disorders 4) phe